NYV1

Symbol: NYV1
Name: New Yeast V-SNARE 1
Alias: MAM2
Entrez gene ID: 850782
Ensembl gene ID: YLR093C
Species: Yeast (Taxid: 4932)

Functional description:
Nyv1p; v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane [Source:SGD;Acc:S000004083] [Ensembl]

Observation:

Deletion of NYV1 cancels out replicative lifespan extension of 0.5% glucose restriction and results under DR also into a shorter replicative lifespan than under AL [18690010; 22622083]. Thus, NYV1 deletion blocks DR-lifespan prolongation [18690010].



Interventions:
  • NYV1 deletion

  • Assays: Replicative Lifespan

    Classification:
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • NYV1 (4932)
  • KLLA0F19448g (28985)
  • AGOS_AGR054C (33169)



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