Figure 3 Increased BubR1 expression protects against spontaneous tumours and extends lifespan

Study: Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.
Species: House mouse
Assay: Organismal
Data: genotype max num

WT 1250 60
T-GFP 882 36
T23 1058 57

T-GFP 882 36
T23 1058 57
Measurments:
  • WT_1250_60
  • T-GFP_882_36
  • T23_1058_57
  • T-GFP_882_36
  • T23_1058_57
  • Comparisons:
  • T-GFP vs. WT
  • T23 vs. WT
  • T23 vs. T-GFP

  • ID exp ctr Manipulation intervention mean median max pvalue T Gender epistasis
    349 T-GFP_882_36 WT_1250_60 - -29.44
    350 T23_1058_57 WT_1250_60 - Bub1b overexpression -15.36
    351 T23_1058_57 T-GFP_882_36 - Bub1b overexpression 19.9546485261
    • 3 comparisons

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