Figure 3. Lifespan Extension by dTsc2 Overexpression Is Dependent on the Concentration of Yeast Extract in the Diet

Study: Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway.
Species: Fruit fly
Assay: Organismal
Data: genotype;diet;mean;num;pvalue
#temperature=29
#background=w1118
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+/da-GAL4;0.1% yeast extract;33;125
da-GAL4/UAS-dTsc2;0.1% yeast extract;30;164;<0.3

+/da-GAL4;0.3% yeast extract;31;139
da-GAL4/UAS-dTsc2;0.3% yeast extract;33;138;<0.03

+/da-GAL4;1% yeast extract;30;182
da-GAL4/UAS-dTsc2;1% yeast extract;34;164;<0.0001

+/da-GAL4;3% yeast extract;28;181
da-GAL4/UAS-dTsc2;3% yeast extract;34;154;<0.0001

+/da-GAL4;9% yeast extract;12;150
da-GAL4/UAS-dTsc2;9% yeast extract;24;156;<0.0001

Measurments:
  • w1118_+/da-GAL4_0.1%_yeast_extract_29_33_125
  • w1118_da-GAL4/UAS-dTsc2_0.1%_yeast_extract_29_30_164
  • w1118_+/da-GAL4_0.3%_yeast_extract_29_31_139
  • w1118_da-GAL4/UAS-dTsc2_0.3%_yeast_extract_29_33_138
  • w1118_+/da-GAL4_1%_yeast_extract_29_30_182
  • w1118_da-GAL4/UAS-dTsc2_1%_yeast_extract_29_34_164
  • w1118_+/da-GAL4_3%_yeast_extract_29_28_181
  • w1118_da-GAL4/UAS-dTsc2_3%_yeast_extract_29_34_154
  • w1118_+/da-GAL4_9%_yeast_extract_29_12_150
  • w1118_da-GAL4/UAS-dTsc2_9%_yeast_extract_29_24_156
  • Comparisons:
  • da-GAL4/UAS-dTsc2 vs. +/da-GAL4
  • da-GAL4/UAS-dTsc2 vs. +/da-GAL4
  • da-GAL4/UAS-dTsc2 vs. +/da-GAL4
  • da-GAL4/UAS-dTsc2 vs. +/da-GAL4
  • da-GAL4/UAS-dTsc2 vs. +/da-GAL4


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