Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains

Study: Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.
Species: Budding yeast
Assay: RLS
Data: genotype mean median max num pvalue
#temperature=30

wt 26.3 26 59 425 -
idh1 32.6 33 60 304 1.66E-14

wt 26.6 26 52 764 -
idh2 30.7 31 60 595 4.10E-11

wt 25.2 23 43 35
atp5 27.3 27 53 55 4.22E-01

wt 25.3 21 40 15 -
coq5 14.3 15 30 15 8.41E-04
Measurments:
  • wild-type_30_26_26_59_425
  • idh1_30_32_33_60_304
  • wild-type_30_26_26_52_764
  • idh2_30_30_31_60_595
  • wild-type_30_25_23_43_35
  • atp5_30_27_27_53_55
  • wild-type_30_25_21_40_15
  • coq5_30_14_15_30_15
  • Comparisons:
  • idh1 vs. wild-type
  • idh2 vs. wild-type
  • atp5 vs. wild-type
  • coq5 vs. wild-type

  • ID exp ctr Manipulation intervention mean median max pvalue T Gender epistasis
    112 coq5_30_14_15_30_15 wild-type_30_25_21_40_15 - -43.4782608696 -28.5714285714 -25.0 0.000841 30°C
    109 idh1_30_32_33_60_304 wild-type_30_26_26_59_425 - 23.9543726236 26.9230769231 1.69491525424 1.66e-14 30°C
    110 idh2_30_30_31_60_595 wild-type_30_26_26_52_764 - IDH2 deletion 15.4135338346 19.2307692308 15.3846153846 4.1e-11 30°C
    111 atp5_30_27_27_53_55 wild-type_30_25_23_43_35 - 8.33333333333 17.3913043478 23.2558139535 0.422 30°C
    • 4 comparisons

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