A 1100-bp sequence of mitochondrial DNA is involved in senescence process in Podospora: study of senescent and mutant cultures.

Authors: Koll F; Belcour L; Vierny C

Abstract: In Podospora, senescence is assumed to be caused by the amplification of short sequences of the mitochondrial genome (sen-DNAs). We have characterized a 1100-bp-long mitochondrial DNA sequence which could be directly involved in the phenomenon. Indeed, by hybridization experiments, we show that this sequence is both present in all the sen-DNA molecules which originate from the beta region of the mitochondrial chromosome and rearranged in the mitochondrial genome of two mitochondrial mutants selected as resistant to senescence.

Keywords: Ascomycota/*genetics/growth & development; Base Sequence; Chromosome Mapping; DNA Restriction Enzymes; DNA, Mitochondrial/*genetics; Gene Amplification; *Genes, Fungal; Mutation; Nucleic Acid Hybridization; Time Factors

Journal: Plasmid Volume: 14 Issue: 2 Pages: 106-17 Date: Sept. 1, 1985 PMID: 2999848

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Citation:

Koll F, Belcour L, Vierny C (1985) A 1100-bp sequence of mitochondrial DNA is involved in senescence process in Podospora: study of senescent and mutant cultures. Plasmid 14: 106-17.

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