Authors: Tapia N; Han DW; Schöler HR
Abstract: Adult stem cells are responsible for the cellular turnover of many organs, and an impairment in their function leads to aging and disease. In efforts to reverse the process of tissue stem cell aging, we speculate on the promise and challenges of in vivo direct reprogramming strategies.
Keywords: Adult; Adult Stem Cells/*cytology/*physiology; Animals; *Cell Aging; Humans; Regenerative Medicine/*methods|
Journal: Cell stem cell Volume: 10 Issue: 6 Pages: 653-6 Date: June 19, 2012 PMID: 22704502 |
Tapia N, Han DW, Schöler HR (2012) Restoring stem cell function in aged tissues by direct reprogramming? Cell stem cell 10: 653-6.
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