Telomere Length

Created on Dec. 7, 2012, 4:08 p.m. by Hevok & updated by Hevok on May 2, 2013, 4:58 p.m.

Telomere length is a molecular trait strongly correlated with age [2342578; Harley et al. 1990] and exhibits an accelerated rate of decay under environmental stress [15574496; Epel et al. 2004; 16112303; Valdes et al 2005].

References

Harley, C.B., Futcher, A.B., and Greider, C.W. (1990). Telomeres shorten during ageing of human fibroblasts. Nature 345, 458–460.

Epel, E.S., Blackburn, E.H., Lin, J., Dhabhar, F.S., Adler, N.E., Morrow, J.D., and Cawthon, R.M. (2004). Accelerated telomere shortening in response to life stress. Proc. Natl. Acad. Sci. USA 101, 17312–17315.

Valdes, A.M., Andrew, T., Gardner, J.P., Kimura, M., Oelsner, E., Cherkas, L.F., Aviv, A., and Spector, T.D. (2005). Obesity, cigarette smoking, and telomere length in women. Lancet 366, 662–664.

long-telomeres.jpg

Tags: telomeres, aging, genome, chromosome
Parent: Aging
Children: Telomere Test

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