Age-related Muscle Decline Slowed by Drug

Created on Oct. 1, 2012, 11:40 p.m. by Hevok & updated by Hevok on May 2, 2013, 4:55 p.m.

The decline in muscle repair can be halted by a common drug. Each muscle harbours a reservoir on dormant stem cells, which upon injury repair any damage by dividing in new muscle fibers. Some of these cells replenish the poll after repair. Normally, the number of dormant stem cells present in the pool reduces with age. Old muscles contain high levels of FGF2. Administrating a common FGF2 inhibitor drug inhibits the decline in the number of muscle stem cells in mice [http://www.biocompare.com/Life-Science-News/121942-Scientists-Make-Old-Muscles-Young-Again-In-Attempt-To-Combat-Aging/].

muscle-stem-cells.jpg

Tags: aging, drug, growth factor, regeneration
Parent: News

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