E2 / E3 / E4

Polymorphism: E2 / E3 / E4






Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )

  • Ethnicity: French
    Age of cases: centenarians 100th year or beyond, mean age 103.1
    Shorter lived allele: E4

    Statistics
    - Number of cases/controls: 560 vs 560 (initial)
    - p-value: 1.2e-08 [1.20E-08]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR-RFLP

    Reference:
    11280044: A study of French centenarians: are ACE and APOE associated with longevity?

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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