rs2542052

Polymorphism: rs2542052
rs2542052 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 11q23.3

Factor:
- Symbol: APOC3
- Name: apolipoprotein C-III
- Entrez ID: 345
- Ensembl ID: ENSG00000110245


Description:

A multilocus PCR for 66 polymorphisms was performed in Askenazi Jews and found a significant correlation with longevity for the rs2542052 poymorphism.

Ethnicity: Ashkenazi Jewish
Age of cases: Mean age 98.2
Shorter lived allele: A
Finding: Positive

Statistics
- Number of cases/controls: Centenarians (n = 213) their offspring (n = 216) vs 258 (initial)
- p-value: 0.0001
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Technology: Multilocus PCR

Reference:
16602826: Lipoprotein genotype and conserved pathway for exceptional longevity in humans.

Choice: Curate
Created: June 30, 2013, midnight
Updated: July 30, 2013, 6:01 p.m.

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