rs4936894

Polymorphism: rs4936894
rs4936894 ( SNPedia | 23andMe )

Location: 11q24.1

Factor:
- Symbol: VWA5A
- Name: von Willebrand factor A domain containing 5A
- Entrez ID: 4013
- Ensembl ID: ENSG00000110002

Factors:
  • VWA5A von Willebrand factor A domain containing 5A ( 4013 / ENSG00000110002 )


  • Description:

    Meta-analysis (with interesting experimental design: follow-up rather then case-control study. Recomended for additional consideration

    Ethnicity: American
    Shorter lived allele: A

    Statistics
    - Number of cases/controls: 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) (initial) | Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project (replication)
    - Odds ratio: 1.1074
    - p-value: 3.38e-07 [0.000000338]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Version 3 Illumina Infinium II HumanHap550 SNP chip array, Illumina 370CNV, Affymetrix GeneChip SNP Array 6.0, Illumina 370CNV, Illumina 550K, Illumina 550K, Illumina Human1M-Duo, Affymetrix SNP Array 6.0, respectively.

    Reference:
    21782286: A genome-wide association study of aging.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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