Denigma

Dgat1 knockout

Factor: Dgat1
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Deficiency in Dagat1 promotes leanless and extends mean, median and oldest 10% survival by 23, 26 and 9% without limiting food intake [22291164].

Mean: +23
Median: +26

References:
  • 22291164: Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.


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