Denigma

kuk Overexpression

Species: Fruit fly (Taxid: 7227)
Factor: kuk
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of kugelkern in the adult muscle results in a 60% reduction of mean lifespan [18494863].

Mean: -60

References:
  • 18494863: The farnesylated nuclear proteins KUGELKERN and LAMIN B promote aging-like phenotypes in Drosophila flies.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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