Denigma

bsk RNAi

Species: Fruit fly (Taxid: 7227)
Factor:
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference of bsk in intestinal stem cells, results in short lived mutants with impaired intestinal homeostasis and tissue regeneration. The mean lifespan of males is 16.4% lower and those of female is reduced by 10.2% [20976250].

Mean: -10.2 to -16.4

References:
  • 20976250: Lifespan extension by preserving proliferative homeostasis in Drosophila.


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