Denigma

Sirt6 RNAi

Species: Fruit fly (Taxid: 7227)
Factor:
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Decreased expression of Sirt6 by RNA interference causes lethality during development. Sirt6 silencing in neurons shortens mean lifespan by 20% [17159295].

Mean: -20

References:
  • 17159295: Involvement of Drosophila Sir2-like genes in the regulation of life span.


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