Genome-wide analysis of miRNA expression in brain aging in primates


Aging in the cortex and cerebrellum of humans, chimpanzees and rhesus macaques is accompyned with a global miRNA downregulation, while a small subset of miRNAs is selectively upregulated. miR-144 is highly conserved and associated with aging progression [http://www.ncbi.nlm.nih.gov/pubmed/20451302].



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